Hong Qi

Latest

• Caspase-1 and Gasdermin D Afford the Optimal Targets with Distinct Switching Strategies in NLRP1b Inflammasome-Induced Cell Death
• Network modeling-based identification of the switching targets between pyroptosis and secondary pyroptosis
• Quantifying the optimal strategy of population control of quorum sensing network in Escherichia coli
• Cell death modes are specified by the crosstalk dynamics within pyroptotic and apoptotic signaling
• Dual mechanisms of Bcl-2 regulation in IP3-receptor-mediated Ca2+ release: A computational study
• Biphasic regulation of transcriptional surge generated by the gene feedback loop in a two-component system
• RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes
• Roles of four feedback loops in mitochondrial permeability transition pore opening induced by Ca^{2+} and reactive oxygen species
• The Oscillation Amplitude, Not the Frequency of Cytosolic Calcium, Regulates Apoptosis Induction
• The Oscillation Amplitude, Not the Frequency of Cytosolic Calcium, Regulates Apoptosis Induction
• Roles of four feedback loops in mitochondrial permeability transition pore opening induced by Ca^{2+} and reactive oxygen species
• Data-Driven Modeling Identifies TIRAP-Independent MyD88 Activation Complex and Myddosome Assembly Strategy in LPS/TLR4 Signaling
• Optimal pathways for the assembly of the Apaf-1 cytochrome c complex into apoptosome
• Biexponential distribution of open times of a toy channel model
• Comparison of gating dynamics of different IP3 R channels with immune algorithm searching for channel parameter distributions
• Suppressing effect of Ca2+ blips on puff amplitudes by inhibiting channels to prevent recovery
• Synonymous mutations in oncogenesis and apoptosis versus survival unveiled by network modeling
• 钙离子通道和钙信号震荡模型研究
• Alzheimer’s disease via enhanced calcium signaling caused by the decrease of endoplasmic reticulum–mitochondrial distance
• Optimal microdomain crosstalk between endoplasmic reticulum and mitochondria for Ca21 oscillation
• Enhanced multiple vibrational resonances by Na1 and K1 dynamics in a neuron model