Zhiyong Yin

Latest

• The spring-like effect of microRNA-31 in balancing inflammatory and regenerative responses in colitis
• Caspase-1 and Gasdermin D Afford the Optimal Targets with Distinct Switching Strategies in NLRP1b Inflammasome-Induced Cell Death
• Network modeling-based identification of the switching targets between pyroptosis and secondary pyroptosis
• Oscillations Governed by the Incoherent Dynamics in Necroptotic Signaling
• Cell death modes are specified by the crosstalk dynamics within pyroptotic and apoptotic signaling
• Biphasic regulation of transcriptional surge generated by the gene feedback loop in a two-component system
• RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes
• Data-Driven Modeling Identifies TIRAP-Independent MyD88 Activation Complex and Myddosome Assembly Strategy in LPS/TLR4 Signaling
• Optimal pathways for the assembly of the Apaf-1 cytochrome c complex into apoptosome